Author: Obinna Allison
Allison, Obinna, 2024 Cloning Heterologous Proteins for the in vitro Biochemical Characterization of Enzymes Involved in the Synthesis of Cell Wall Polysaccharides, Flinders University, College of Medicine and Public Health
Terms of Use: This electronic version is (or will be) made publicly available by Flinders University in accordance with its open access policy for student theses. Copyright in this thesis remains with the author. You may use this material for uses permitted under the Copyright Act 1968. If you are the owner of any included third party copyright material and/or you believe that any material has been made available without permission of the copyright owner please contact copyright@flinders.edu.au with the details.
Both human and plant pathogenic fungi have serious economic health and social
implications Rhizopus arrhizus is a filamentous fungus and a common cause of
mucormycosis a severe fungal infection that affects immunocompromised individuals and
manifests as fulminant fungal sinusitis for which there is limited treatment The cell wall is a
vital structural element in fungal organisms, providing both support and protection It primarily
consists of polysaccharides like chitin and glucans that determine fungal integrity and
virulence Our research endeavours to unravel the complexity of the fungal cell wall by
shedding light on the functions of cell wall biosynthetic enzymes These enzymes have diverse
biological functions with promising potential as targets for new antifungal strategies
Keywords: Cell wall, enzymes, PCR, plasmid
Subject: Biotechnology thesis
Thesis type: Masters
Completed: 2024
School: College of Medicine and Public Health
Supervisor: Caterina Selva